The monothiol glutaredoxin GrxD is essential for sensing iron starvation in Aspergillus fumigatus

Efficient adaptation to iron starvation is an essential virulence determinant of the most common human mold pathogen, Aspergillus fumigatus. Here, we demonstrate that the cytosolic monothiol glutaredoxin GrxD plays an essential role in iron sensing in this fungus. Our studies revealed that (i) GrxD...

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Detalles Bibliográficos
Autores principales: Misslinger, Matthias, Scheven, Mareike Thea, Hortschansky, Peter, López-Berges, Manuel Sánchez, Heiss, Katharina, Beckmann, Nicola, Heigl, Thomas, Hermann, Martin, Krüger, Thomas, Kniemeyer, Olaf, Brakhage, Axel A., Haas, Hubertus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6762210/
https://www.ncbi.nlm.nih.gov/pubmed/31525190
http://dx.doi.org/10.1371/journal.pgen.1008379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6762210/
https://www.ncbi.nlm.nih.gov/pubmed/31525190
http://dx.doi.org/10.1371/journal.pgen.1008379

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