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Chromosome-wide co-fluctuation of stochastic gene expression in mammalian cells

Gene expression is subject to stochastic noise, but to what extent and by which means such stochastic variations are coordinated among different genes are unclear. We hypothesize that neighboring genes on the same chromosome co-fluctuate in expression because of their common chromatin dynamics, and...

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Detalles Bibliográficos
Autores principales: Sun, Mengyi, Zhang, Jianzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6762216/
https://www.ncbi.nlm.nih.gov/pubmed/31525198
http://dx.doi.org/10.1371/journal.pgen.1008389