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Type I IFN protects cancer cells from CD8(+) T cell–mediated cytotoxicity after radiation

Treatment of tumors with ionizing radiation stimulates an antitumor immune response partly dependent on induction of IFNs. These IFNs directly enhance dendritic cell and CD8(+) T cell activity. Here we show that resistance to an effective antitumor immune response is also a result of IFN signaling i...

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Detalles Bibliográficos
Autores principales:	Chen, Jianzhou, Cao, Yunhong, Markelc, Bostjan, Kaeppler, Jakob, Vermeer, Jenny A.F., Muschel, Ruth J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763250/ https://www.ncbi.nlm.nih.gov/pubmed/31483286 http://dx.doi.org/10.1172/JCI127458

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