Blocking COX-2 induces apoptosis and inhibits cell proliferation via the Akt/survivin- and Akt/ID3 pathway in low-grade-glioma

Approximately half of surgically-treated patients with low-grade-glioma (LGG) suffer recurrence or metastasis. Currently there is no effective drug treatment. While the selective COX-2 inhibitor celecoxib showed anti-neoplastic activity against several malignant tumors, its effects against LGG remai...

Descripción completa

Detalles Bibliográficos
Autores principales: Sato, Aya, Mizobuchi, Yoshifumi, Nakajima, Kohei, Shono, Kenji, Fujihara, Toshitaka, Kageji, Teruyoshi, Kitazato, Keiko, Matsuzaki, Kazuhito, Mure, Hideo, Kuwayama, Kazuyuki, Sumi, Akiko, Saya, Hideyuki, Sampetrean, Oltea, Nagahirao, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Laboratory Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763415/
https://www.ncbi.nlm.nih.gov/pubmed/28283800
http://dx.doi.org/10.1007/s11060-017-2380-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763415/
https://www.ncbi.nlm.nih.gov/pubmed/28283800
http://dx.doi.org/10.1007/s11060-017-2380-5

Ejemplares similares