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LIM homeodomain transcription factor Isl1 affects urethral epithelium differentiation and apoptosis via Shh

Urethral hypoplasia, including failure of urethral tube closure, is one of the common phenotypes observed in hereditary human disorders, the mechanism of which remains unclear. The present study was thus designed to study the expression, functions, and related mechanisms of the LIM homeobox transcri...

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Detalles Bibliográficos
Autores principales: Su, Tiantian, Liu, Hui, Zhang, Di, Xu, Guojin, Liu, Jiali, Evans, Sylvia M., Pan, Jirong, Cui, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763423/
https://www.ncbi.nlm.nih.gov/pubmed/31558700
http://dx.doi.org/10.1038/s41419-019-1952-z