Methionine in a protein hydrophobic core drives tight interactions required for assembly of spider silk

Web spiders connect silk proteins, so-called spidroins, into fibers of extraordinary toughness. The spidroin N-terminal domain (NTD) plays a pivotal role in this process: it polymerizes spidroins through a complex mechanism of dimerization. Here we analyze sequences of spidroin NTDs and find an unus...

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Detalles Bibliográficos
Autores principales: Heiby, Julia C., Goretzki, Benedikt, Johnson, Christopher M., Hellmich, Ute A., Neuweiler, Hannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763431/
https://www.ncbi.nlm.nih.gov/pubmed/31558722
http://dx.doi.org/10.1038/s41467-019-12365-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763431/
https://www.ncbi.nlm.nih.gov/pubmed/31558722
http://dx.doi.org/10.1038/s41467-019-12365-5

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