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Bidirectional in vivo structural dendritic spine plasticity revealed by two-photon glutamate uncaging in the mouse neocortex

Most excitatory synapses in the brain form on dendritic spines. Two-photon uncaging of glutamate is widely utilized to characterize the structural plasticity of dendritic spines in brain slice preparations in vitro. In the present study, glutamate uncaging was used to investigate spine plasticity, f...

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Detalles Bibliográficos
Autores principales: Noguchi, Jun, Nagaoka, Akira, Hayama, Tatsuya, Ucar, Hasan, Yagishita, Sho, Takahashi, Noriko, Kasai, Haruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763442/
https://www.ncbi.nlm.nih.gov/pubmed/31558759
http://dx.doi.org/10.1038/s41598-019-50445-0