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Processing of a single ribonucleotide embedded into DNA by human nucleotide excision repair and DNA polymerase η

DNA polymerases often incorporate non-canonical nucleotide, i.e., ribonucleoside triphosphates into the genomic DNA. Aberrant accumulation of ribonucleotides in the genome causes various cellular abnormalities. Here, we show the possible role of human nucleotide excision repair (NER) and DNA polymer...

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Detalles Bibliográficos
Autores principales: Sassa, Akira, Tada, Haruto, Takeishi, Ayuna, Harada, Kaho, Suzuki, Megumi, Tsuda, Masataka, Sasanuma, Hiroyuki, Takeda, Shunichi, Sugasawa, Kaoru, Yasui, Manabu, Honma, Masamitsu, Ura, Kiyoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763444/
https://www.ncbi.nlm.nih.gov/pubmed/31558768
http://dx.doi.org/10.1038/s41598-019-50421-8