Argonaute bypasses cellular obstacles without hindrance during target search

Argonaute (Ago) proteins are key players in both gene regulation (eukaryotes) and host defense (prokaryotes). Acting on single-stranded nucleic-acid substrates, Ago relies on base pairing between a small nucleic-acid guide and its complementary target sequences for specificity. To efficiently scan n...

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Detalles Bibliográficos
Autores principales: Cui, Tao Ju, Klein, Misha, Hegge, Jorrit W., Chandradoss, Stanley D., van der Oost, John, Depken, Martin, Joo, Chirlmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763497/
https://www.ncbi.nlm.nih.gov/pubmed/31558728
http://dx.doi.org/10.1038/s41467-019-12415-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763497/
https://www.ncbi.nlm.nih.gov/pubmed/31558728
http://dx.doi.org/10.1038/s41467-019-12415-y

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