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Heterogeneity of HBV-Specific CD8(+) T-Cell Failure: Implications for Immunotherapy

Chronic hepatitis B virus (HBV) infection is a major global health burden affecting around 257 million people worldwide. The consequences of chronic HBV infection include progressive liver damage, liver cirrhosis, and hepatocellular carcinoma. Although current direct antiviral therapies successfully...

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Detalles Bibliográficos
Autores principales: Heim, Kathrin, Neumann-Haefelin, Christoph, Thimme, Robert, Hofmann, Maike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763562/
https://www.ncbi.nlm.nih.gov/pubmed/31620140
http://dx.doi.org/10.3389/fimmu.2019.02240