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Heterogeneity of HBV-Specific CD8(+) T-Cell Failure: Implications for Immunotherapy
Chronic hepatitis B virus (HBV) infection is a major global health burden affecting around 257 million people worldwide. The consequences of chronic HBV infection include progressive liver damage, liver cirrhosis, and hepatocellular carcinoma. Although current direct antiviral therapies successfully...
Autores principales: | Heim, Kathrin, Neumann-Haefelin, Christoph, Thimme, Robert, Hofmann, Maike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763562/ https://www.ncbi.nlm.nih.gov/pubmed/31620140 http://dx.doi.org/10.3389/fimmu.2019.02240 |
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