Cargando…

Phospho-Protein Arrays as Effective Tools for Screening Possible Targets for Kinase Inhibitors and Their Use in Precision Pediatric Oncology

The specific targeting of signal transduction by low-molecular-weight inhibitors or monoclonal antibodies represents a very promising personalized treatment strategy in pediatric oncology. In this study, we present the successful and clinically relevant use of commercially available phospho-protein...

Descripción completa

Detalles Bibliográficos
Autores principales: Neradil, Jakub, Kyr, Michal, Polaskova, Kristyna, Kren, Leos, Macigova, Petra, Skoda, Jan, Sterba, Jaroslav, Veselska, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763615/
https://www.ncbi.nlm.nih.gov/pubmed/31616636
http://dx.doi.org/10.3389/fonc.2019.00930