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Phospho-Protein Arrays as Effective Tools for Screening Possible Targets for Kinase Inhibitors and Their Use in Precision Pediatric Oncology
The specific targeting of signal transduction by low-molecular-weight inhibitors or monoclonal antibodies represents a very promising personalized treatment strategy in pediatric oncology. In this study, we present the successful and clinically relevant use of commercially available phospho-protein...
Autores principales: | Neradil, Jakub, Kyr, Michal, Polaskova, Kristyna, Kren, Leos, Macigova, Petra, Skoda, Jan, Sterba, Jaroslav, Veselska, Renata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763615/ https://www.ncbi.nlm.nih.gov/pubmed/31616636 http://dx.doi.org/10.3389/fonc.2019.00930 |
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