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Elimination of the four extracellular matrix molecules tenascin-C, tenascin-R, brevican and neurocan alters the ratio of excitatory and inhibitory synapses

The synaptic transmission in the mammalian brain is not limited to the interplay between the pre- and the postsynapse of neurons, but involves also astrocytes as well as extracellular matrix (ECM) molecules. Glycoproteins, proteoglycans and hyaluronic acid of the ECM pervade the pericellular environ...

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Detalles Bibliográficos
Autores principales: Gottschling, Christine, Wegrzyn, David, Denecke, Bernd, Faissner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763627/
https://www.ncbi.nlm.nih.gov/pubmed/31558805
http://dx.doi.org/10.1038/s41598-019-50404-9