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Switching From a Protease Inhibitor–based Regimen to a Dolutegravir-based Regimen: A Randomized Clinical Trial to Determine the Effect on Peripheral Blood and Ileum Biopsies From Antiretroviral Therapy–suppressed Human Immunodeficiency Virus–infected Individuals

BACKGROUND: Optimization of combination antiretroviral therapy (cART) can impact the human immunodeficiency virus (HIV) reservoir. We evaluated the effect on the HIV reservoir in peripheral blood and ileum biopsies in patients switching from boosted protease inhibitor (PI/r)–based therapy to doluteg...

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Detalles Bibliográficos
Autores principales: Morón-López, Sara, Navarro, Jordi, Jimenez, Montse, Rutsaert, Sofie, Urrea, Víctor, Puertas, Maria C, Torrella, Ariadna, De Clercq, Laura, Ribas, Bibiana Planas, Gálvez, Cristina, Salgado, Maria, Vandekerckhove, Linos, Blanco, Julià, Crespo, Manel, Martinez-Picado, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763634/
https://www.ncbi.nlm.nih.gov/pubmed/30590412
http://dx.doi.org/10.1093/cid/ciy1095