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Morin Hydrate Inhibits TREM-1/TLR4-Mediated Inflammatory Response in Macrophages and Protects Against Carbon Tetrachloride-Induced Acute Liver Injury in Mice

This study aims to investigate the protective effects of morin hydrate (MH) against acute liver injury induced by carbon tetrachloride (CCl(4)) in mice and to elucidate the possible molecular mechanism of action. Mice were pretreated with MH (50 mg/kg body weight) or vehicle by oral gavage once dail...

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Detalles Bibliográficos
Autores principales: Li, Xi, Yao, Qunyan, Huang, Jiying, Jin, Qianwen, Xu, Beili, Chen, Fangyuan, Tu, Chuantao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763683/
https://www.ncbi.nlm.nih.gov/pubmed/31616301
http://dx.doi.org/10.3389/fphar.2019.01089