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Lethal Infection of Lassa Virus Isolated from a Human Clinical Sample in Outbred Guinea Pigs without Adaptation

Lassa virus (LASV), a member of the family Arenaviridae, is the causative agent of Lassa fever. Lassa virus is endemic in West African countries, such as Nigeria, Guinea, Liberia, and Sierra Leone, and causes outbreaks annually. Lassa fever onset begins with “flu-like” symptoms and may develop into...

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Detalles Bibliográficos
Autores principales: Maruyama, Junki, Manning, John T., Mateer, Elizabeth J., Sattler, Rachel, Bukreyeva, Natalya, Huang, Cheng, Paessler, Slobodan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763766/
https://www.ncbi.nlm.nih.gov/pubmed/31554720
http://dx.doi.org/10.1128/mSphere.00428-19