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Prioritization of candidate cancer drugs based on a drug functional similarity network constructed by integrating pathway activities and drug activities

Due to the speed, efficiency, relative risk, and lower costs compared to traditional drug discovery, the prioritization of candidate drugs for repurposing against cancers of interest has attracted the attention of experts in recent years. Herein, we present a powerful computational approach, termed...

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Detalles Bibliográficos
Autores principales: Di, Jieyi, Zheng, Baotong, Kong, Qingfei, Jiang, Ying, Liu, Siyao, Yang, Yang, Han, Xudong, Sheng, Yuqi, Zhang, Yunpeng, Cheng, Liang, Han, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763777/
https://www.ncbi.nlm.nih.gov/pubmed/31408580
http://dx.doi.org/10.1002/1878-0261.12564