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Cre-loxP Reporter Mouse Reveals Stochastic Activity of the Foxp3 Promoter
Mouse models that combine specific loxP-flanked gene sequences with Cre recombinase expressed from cell-regulated promoters have become important tools to investigate gene function. Critically however, expression of Cre recombinase may not always be restricted to the target cell or tissue of interes...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763954/ https://www.ncbi.nlm.nih.gov/pubmed/31616418 http://dx.doi.org/10.3389/fimmu.2019.02228 |