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Cre-loxP Reporter Mouse Reveals Stochastic Activity of the Foxp3 Promoter

Mouse models that combine specific loxP-flanked gene sequences with Cre recombinase expressed from cell-regulated promoters have become important tools to investigate gene function. Critically however, expression of Cre recombinase may not always be restricted to the target cell or tissue of interes...

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Detalles Bibliográficos
Autores principales: Bittner-Eddy, Peter D., Fischer, Lori A., Costalonga, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763954/
https://www.ncbi.nlm.nih.gov/pubmed/31616418
http://dx.doi.org/10.3389/fimmu.2019.02228