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Butyrate Does Not Protect Against Inflammation-induced Loss of Epithelial Barrier Function and Cytokine Production in Primary Cell Monolayers From Patients With Ulcerative Colitis

BACKGROUND AND AIMS: In vitro studies using immortalised cancer cell lines showed that butyrate has an overall positive effect on epithelial barrier integrity, but the physiological relevance of cancer cell lines is limited. We developed epithelial monolayers from human tissue samples of patients wi...

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Detalles Bibliográficos
Autores principales: Vancamelbeke, Maaike, Laeremans, Thessa, Vanhove, Wiebe, Arnauts, Kaline, Ramalho, Anabela Santo, Farré, Ricard, Cleynen, Isabelle, Ferrante, Marc, Vermeire, Séverine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764103/
https://www.ncbi.nlm.nih.gov/pubmed/30919886
http://dx.doi.org/10.1093/ecco-jcc/jjz064