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Butyrate Does Not Protect Against Inflammation-induced Loss of Epithelial Barrier Function and Cytokine Production in Primary Cell Monolayers From Patients With Ulcerative Colitis
BACKGROUND AND AIMS: In vitro studies using immortalised cancer cell lines showed that butyrate has an overall positive effect on epithelial barrier integrity, but the physiological relevance of cancer cell lines is limited. We developed epithelial monolayers from human tissue samples of patients wi...
Autores principales: | Vancamelbeke, Maaike, Laeremans, Thessa, Vanhove, Wiebe, Arnauts, Kaline, Ramalho, Anabela Santo, Farré, Ricard, Cleynen, Isabelle, Ferrante, Marc, Vermeire, Séverine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764103/ https://www.ncbi.nlm.nih.gov/pubmed/30919886 http://dx.doi.org/10.1093/ecco-jcc/jjz064 |
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