TLR4-RelA-miR-30a signal pathway regulates Th17 differentiation during experimental autoimmune encephalomyelitis development

BACKGROUND: Toll-like receptor 4 (TLR4) is well known for activating the innate immune system; however, it is also highly expressed in adaptive immune cells, such as CD4(+) T-helper 17 (Th17) cells, which play a key role in multiple sclerosis (MS) pathology. However, the function and governing mecha...

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Detalles Bibliográficos
Autores principales: Qu, Xuebin, Han, Jingjing, Zhang, Ying, Wang, Xingqi, Fan, Hongbin, Hua, Fang, Yao, Ruiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764145/
https://www.ncbi.nlm.nih.gov/pubmed/31561751
http://dx.doi.org/10.1186/s12974-019-1579-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764145/
https://www.ncbi.nlm.nih.gov/pubmed/31561751
http://dx.doi.org/10.1186/s12974-019-1579-0

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