Rational Design of Fluorogenic and Spontaneously Blinking Labels for Super-Resolution Imaging

[Image: see text] Rhodamine dyes exist in equilibrium between a fluorescent zwitterion and a nonfluorescent lactone. Tuning this equilibrium toward the nonfluorescent lactone form can improve cell-permeability and allow creation of “fluorogenic” compounds—ligands that shift to the fluorescent zwitte...

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Detalles Bibliográficos
Autores principales: Zheng, Qinsi, Ayala, Anthony X., Chung, Inhee, Weigel, Aubrey V., Ranjan, Anand, Falco, Natalie, Grimm, Jonathan B., Tkachuk, Ariana N., Wu, Carl, Lippincott-Schwartz, Jennifer, Singer, Robert H., Lavis, Luke D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764213/
https://www.ncbi.nlm.nih.gov/pubmed/31572787
http://dx.doi.org/10.1021/acscentsci.9b00676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764213/
https://www.ncbi.nlm.nih.gov/pubmed/31572787
http://dx.doi.org/10.1021/acscentsci.9b00676

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