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Rational Design of Fluorogenic and Spontaneously Blinking Labels for Super-Resolution Imaging
[Image: see text] Rhodamine dyes exist in equilibrium between a fluorescent zwitterion and a nonfluorescent lactone. Tuning this equilibrium toward the nonfluorescent lactone form can improve cell-permeability and allow creation of “fluorogenic” compounds—ligands that shift to the fluorescent zwitte...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764213/ https://www.ncbi.nlm.nih.gov/pubmed/31572787 http://dx.doi.org/10.1021/acscentsci.9b00676 |