Saikosaponin-d Inhibits the Hepatoma Cells and Enhances Chemosensitivity Through SENP5-Dependent Inhibition of Gli1 SUMOylation Under Hypoxia

Chemosensitivity is one of the key factors affecting the therapeutic effect on cancer, but the clinical application of corresponding drugs is rare. Hypoxia, a common feature of many solid tumors, including hepatocellular carcinoma (HCC), has been associated with resistance to chemotherapy in part th...

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Detalles Bibliográficos
Autores principales: Zhang, Chun-Yan, Jiang, Zhong-Min, Ma, Xiao-Fang, Li, Yue, Liu, Xiao-Zhi, Li, Li-Li, Wu, Wen-Han, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764240/
https://www.ncbi.nlm.nih.gov/pubmed/31616295
http://dx.doi.org/10.3389/fphar.2019.01039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764240/
https://www.ncbi.nlm.nih.gov/pubmed/31616295
http://dx.doi.org/10.3389/fphar.2019.01039

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