A perturbed gene network containing PI3K/AKT, RAS/ERK, WNT/β-catenin pathways in leukocytes is linked to ASD genetics and symptom severity

Hundreds of genes are implicated in autism spectrum disorder (ASD) but the mechanisms through which they contribute to ASD pathophysiology remain elusive. Here, we analyzed leukocyte transcriptomics from 1–4 year-old male toddlers with ASD or typical development from the general population. We disco...

Descripción completa

Detalles Bibliográficos
Autores principales: Gazestani, Vahid H., Pramparo, Tiziano, Nalabolu, Srinivasa, Kellman, Benjamin P., Murray, Sarah, Lopez, Linda, Pierce, Karen, Courchesne, Eric, Lewis, Nathan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764590/
https://www.ncbi.nlm.nih.gov/pubmed/31551593
http://dx.doi.org/10.1038/s41593-019-0489-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764590/
https://www.ncbi.nlm.nih.gov/pubmed/31551593
http://dx.doi.org/10.1038/s41593-019-0489-x

Ejemplares similares