HMGB1 mediates the development of tendinopathy due to mechanical overloading

Mechanical overloading is a major cause of tendinopathy, but the underlying pathogenesis of tendinopathy is unclear. Here we report that high mobility group box1 (HMGB1) is released to the tendon extracellular matrix and initiates an inflammatory cascade in response to mechanical overloading in a mo...

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Detalles Bibliográficos
Autores principales: Zhao, Guangyi, Zhang, Jianying, Nie, Daibang, Zhou, Yiqin, Li, Feng, Onishi, Kentaro, Billiar, Timothy, Wang, James H-C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764662/
https://www.ncbi.nlm.nih.gov/pubmed/31560698
http://dx.doi.org/10.1371/journal.pone.0222369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764662/
https://www.ncbi.nlm.nih.gov/pubmed/31560698
http://dx.doi.org/10.1371/journal.pone.0222369

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