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Microbiota of MR1 deficient mice confer resistance against Clostridium difficile infection

Clostridium difficile (Cd) infection (CDI) typically occurs after antibiotic usage perturbs the gut microbiota. Mucosa-associated invariant T cells (MAIT) are found in the gut and their development is dependent on Major histocompatibility complex-related protein 1 (MR1) and the host microbiome. Here...

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Detalles Bibliográficos
Autores principales: Smith, Ashley D., Foss, Elissa D., Zhang, Irma, Hastie, Jessica L., Giordano, Nicole P., Gasparyan, Lusine, VinhNguyen, Lam Phuc, Schubert, Alyxandria M., Prasad, Deepika, McMichael, Hannah L., Sun, Jinchun, Beger, Richard D., Simonyan, Vahan, Cowley, Siobhán C., Carlson, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764671/
https://www.ncbi.nlm.nih.gov/pubmed/31560732
http://dx.doi.org/10.1371/journal.pone.0223025