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IGFBP2 promotes immunosuppression associated with its mesenchymal induction and FcγRIIB phosphorylation in glioblastoma

Immunotherapy shows a promise for treating glioblastoma (GBM), the most malignant and immunosuppressive glioma. The mesenchymal phenotype of cancer cells was frequently reported to be associated with their induction of immunosuppression within the cancer microenvironment. Overexpressed insulin-like...

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Detalles Bibliográficos
Autores principales: Liu, Yunmian, Song, Chunyan, Shen, Faping, Zhang, Jing, Song, Sonya Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764691/
https://www.ncbi.nlm.nih.gov/pubmed/31560714
http://dx.doi.org/10.1371/journal.pone.0222999