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Regulatory interaction between the ZPBP2-ORMDL3/Zpbp2-Ormdl3 region and the circadian clock

Genome-wide association study (GWAS) loci for several immunity-mediated diseases (early onset asthma, inflammatory bowel disease (IBD), primary biliary cholangitis, and rheumatoid arthritis) map to chromosomal region 17q12-q21. The predominant view is that association between 17q12-q21 alleles and i...

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Detalles Bibliográficos
Autores principales: Chang, Matthew L., Moussette, Sanny, Gamero-Estevez, Enrique, Gálvez, José Héctor, Chiwara, Victoria, Gupta, Indra R., Ryan, Aimee K., Naumova, Anna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764692/
https://www.ncbi.nlm.nih.gov/pubmed/31560728
http://dx.doi.org/10.1371/journal.pone.0223212