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Confounding by indication of the safety of de-escalation in community-acquired pneumonia: A simulation study embedded in a prospective cohort

Observational studies have demonstrated that de-escalation of antimicrobial therapy is independently associated with lower mortality. This most probably results from confounding by indication. Reaching clinical stability is associated with the decision to de-escalate and with survival. However, stud...

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Detalles Bibliográficos
Autores principales: van Heijl, Inger, Schweitzer, Valentijn A., Boel, C. H. Edwin, Oosterheert, Jan Jelrik, Huijts, Susanne M., Dorigo-Zetsma, Wendelien, van der Linden, Paul D., Bonten, Marc J. M., van Werkhoven, Cornelis H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764693/
https://www.ncbi.nlm.nih.gov/pubmed/31560686
http://dx.doi.org/10.1371/journal.pone.0218062