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Confounding by indication of the safety of de-escalation in community-acquired pneumonia: A simulation study embedded in a prospective cohort
Observational studies have demonstrated that de-escalation of antimicrobial therapy is independently associated with lower mortality. This most probably results from confounding by indication. Reaching clinical stability is associated with the decision to de-escalate and with survival. However, stud...
Autores principales: | van Heijl, Inger, Schweitzer, Valentijn A., Boel, C. H. Edwin, Oosterheert, Jan Jelrik, Huijts, Susanne M., Dorigo-Zetsma, Wendelien, van der Linden, Paul D., Bonten, Marc J. M., van Werkhoven, Cornelis H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764693/ https://www.ncbi.nlm.nih.gov/pubmed/31560686 http://dx.doi.org/10.1371/journal.pone.0218062 |
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