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Slow depressurization following intradiscal injection leads to injectate leakage in a large animal model
Needle injection has been indicated as the most practical method of delivering therapeutic agents to the intervertebral disc due to the disc's largely avascular nature. As the disc is characterized by both high stiffness and low permeability, injection requires substantial pressure, which may n...
Autores principales: | Varden, Lara J., Nguyen, Duc T., Michalek, Arthur J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764785/ https://www.ncbi.nlm.nih.gov/pubmed/31572978 http://dx.doi.org/10.1002/jsp2.1061 |
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