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Leader cell PLCγ1 activation during keratinocyte collective migration is induced by EGFR localization and clustering

Re‐epithelialization is a critical step in wound healing and results from the collective migration of keratinocytes. Previous work demonstrated that immobilized, but not soluble, epidermal growth factor (EGF) resulted in leader cell‐specific activation of phospholipase C gamma 1 (PLCγ1) in HaCaT ker...

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Detalles Bibliográficos
Autores principales: Kim, Chloe S., Yang, Xinhai, Jacobsen, Sarah, Masters, Kristyn S., Kreeger, Pamela K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764804/
https://www.ncbi.nlm.nih.gov/pubmed/31572796
http://dx.doi.org/10.1002/btm2.10138