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Cell-autonomous regulation of epithelial cell quiescence by calcium channel Trpv6

Epithelial homeostasis and regeneration require a pool of quiescent cells. How the quiescent cells are established and maintained is poorly understood. Here, we report that Trpv6, a cation channel responsible for epithelial Ca(2+) absorption, functions as a key regulator of cellular quiescence. Gene...

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Detalles Bibliográficos
Autores principales: Xin, Yi, Malick, Allison, Hu, Meiqin, Liu, Chengdong, Batah, Heya, Xu, Haoxing, Duan, Cunming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764821/
https://www.ncbi.nlm.nih.gov/pubmed/31526479
http://dx.doi.org/10.7554/eLife.48003