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Mamo decodes hierarchical temporal gradients into terminal neuronal fate

Temporal patterning is a seminal method of expanding neuronal diversity. Here we unravel a mechanism decoding neural stem cell temporal gene expression and transforming it into discrete neuronal fates. This mechanism is characterized by hierarchical gene expression. First, Drosophila neuroblasts exp...

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Detalles Bibliográficos
Autores principales: Liu, Ling-Yu, Long, Xi, Yang, Ching-Po, Miyares, Rosa L, Sugino, Ken, Singer, Robert H, Lee, Tzumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764822/
https://www.ncbi.nlm.nih.gov/pubmed/31545163
http://dx.doi.org/10.7554/eLife.48056