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Mamo decodes hierarchical temporal gradients into terminal neuronal fate
Temporal patterning is a seminal method of expanding neuronal diversity. Here we unravel a mechanism decoding neural stem cell temporal gene expression and transforming it into discrete neuronal fates. This mechanism is characterized by hierarchical gene expression. First, Drosophila neuroblasts exp...
Autores principales: | Liu, Ling-Yu, Long, Xi, Yang, Ching-Po, Miyares, Rosa L, Sugino, Ken, Singer, Robert H, Lee, Tzumin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764822/ https://www.ncbi.nlm.nih.gov/pubmed/31545163 http://dx.doi.org/10.7554/eLife.48056 |
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