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Cortical tau deposition follows patterns of entorhinal functional connectivity in aging

Tau pathology first appears in the transentorhinal and anterolateral entorhinal cortex (alEC) in the aging brain. The transition to Alzheimer’s disease (AD) is hypothesized to involve amyloid-β (Aβ) facilitated tau spread through neural connections. We contrasted functional connectivity (FC) of alEC...

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Detalles Bibliográficos
Autores principales: Adams, Jenna N, Maass, Anne, Harrison, Theresa M, Baker, Suzanne L, Jagust, William J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764824/
https://www.ncbi.nlm.nih.gov/pubmed/31475904
http://dx.doi.org/10.7554/eLife.49132