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A flexible and parallelizable approach to genome‐wide polygenic risk scores
The heritability of most complex traits is driven by variants throughout the genome. Consequently, polygenic risk scores, which combine information on multiple variants genome‐wide, have demonstrated improved accuracy in genetic risk prediction. We present a new two‐step approach to constructing gen...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764842/ https://www.ncbi.nlm.nih.gov/pubmed/31328830 http://dx.doi.org/10.1002/gepi.22245 |