Cargando…

Structure and chemistry of lysinoalanine crosslinking in the spirochaete flagella hook

The flagellar hook protein FlgE from spirochaete bacteria self-catalyzes the formation of an unusual inter-subunit lysinoalanine (Lal) crosslink that is critical for cell motility. Unlike other known examples of Lal biosynthesis, conserved cysteine and lysine residues in FlgE spontaneously react to...

Descripción completa

Detalles Bibliográficos
Autores principales: Lynch, Michael J., Miller, Michael, James, Milinda, Zhang, Sheng, Zhang, Kai, Li, Chunhao, Charon, Nyles W., Crane, Brian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764852/
https://www.ncbi.nlm.nih.gov/pubmed/31406373
http://dx.doi.org/10.1038/s41589-019-0341-3