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Structure and chemistry of lysinoalanine crosslinking in the spirochaete flagella hook
The flagellar hook protein FlgE from spirochaete bacteria self-catalyzes the formation of an unusual inter-subunit lysinoalanine (Lal) crosslink that is critical for cell motility. Unlike other known examples of Lal biosynthesis, conserved cysteine and lysine residues in FlgE spontaneously react to...
Autores principales: | Lynch, Michael J., Miller, Michael, James, Milinda, Zhang, Sheng, Zhang, Kai, Li, Chunhao, Charon, Nyles W., Crane, Brian R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764852/ https://www.ncbi.nlm.nih.gov/pubmed/31406373 http://dx.doi.org/10.1038/s41589-019-0341-3 |
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