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C/EBPδ protects from radiation-induced intestinal injury and sepsis by suppression of inflammatory and nitrosative stress

Ionizing radiation (IR)-induced intestinal damage is characterized by a loss of intestinal crypt cells, intestinal barrier disruption and translocation of intestinal microflora resulting in sepsis-mediated lethality. We have shown that mice lacking C/EBPδ display IR-induced intestinal and hematopoie...

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Detalles Bibliográficos
Autores principales: Banerjee, Sudip, Fu, Qiang, Shah, Sumit K., Melnyk, Stepan B, Sterneck, Esta, Hauer-Jensen, Martin, Pawar, Snehalata A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764943/
https://www.ncbi.nlm.nih.gov/pubmed/31562350
http://dx.doi.org/10.1038/s41598-019-49437-x