Non-enzymatic roles of human RAD51 at stalled replication forks

The central recombination enzyme RAD51 has been implicated in replication fork processing and restart in response to replication stress. Here, we use a separation-of-function allele of RAD51 that retains DNA binding, but not D-loop activity, to reveal mechanistic aspects of RAD51’s roles in the resp...

Descripción completa

Detalles Bibliográficos
Autores principales: Mason, Jennifer M., Chan, Yuen-Ling, Weichselbaum, Ralph W., Bishop, Douglas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764946/
https://www.ncbi.nlm.nih.gov/pubmed/31562309
http://dx.doi.org/10.1038/s41467-019-12297-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764946/
https://www.ncbi.nlm.nih.gov/pubmed/31562309
http://dx.doi.org/10.1038/s41467-019-12297-0

Ejemplares similares