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Non-enzymatic roles of human RAD51 at stalled replication forks
The central recombination enzyme RAD51 has been implicated in replication fork processing and restart in response to replication stress. Here, we use a separation-of-function allele of RAD51 that retains DNA binding, but not D-loop activity, to reveal mechanistic aspects of RAD51’s roles in the resp...
Autores principales: | Mason, Jennifer M., Chan, Yuen-Ling, Weichselbaum, Ralph W., Bishop, Douglas K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764946/ https://www.ncbi.nlm.nih.gov/pubmed/31562309 http://dx.doi.org/10.1038/s41467-019-12297-0 |
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