Cargando…
Connective tissue fibroblasts from highly regenerative mammals are refractory to ROS-induced cellular senescence
A surveillance system in mammals constantly monitors cell activity to protect against aberrant proliferation in response to damage, injury and oncogenic stress. Here we isolate and culture connective tissue fibroblasts from highly regenerative mammals (Acomys and Oryctolagus) to determine how these...
Autores principales: | Saxena, Sandeep, Vekaria, Hemendra, Sullivan, Patrick G., Seifert, Ashley W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764955/ https://www.ncbi.nlm.nih.gov/pubmed/31562333 http://dx.doi.org/10.1038/s41467-019-12398-w |
Ejemplares similares
-
Decellularization of Dense Regular Connective Tissue—Cellular and Molecular Modification with Applications in Regenerative Medicine
por: Data, Krzysztof, et al.
Publicado: (2023) -
Zebra-Fishing for Regenerative Awakening in Mammals
por: Massoz, Laura, et al.
Publicado: (2021) -
Nectandrin B-mediated activation of the AMPK pathway prevents cellular senescence in human diploid fibroblasts by reducing intracellular ROS levels
por: Jang, Hyun-Jin, et al.
Publicado: (2019) -
Bmi-1 alleviates adventitial fibroblast senescence by eliminating ROS in pulmonary hypertension
por: Li, Kai, et al.
Publicado: (2021) -
Therapeutic Stimulation of Glycolytic ATP Production for Treating ROS-Mediated Cellular Senescence
por: Seledtsov, Victor I., et al.
Publicado: (2022)