Cargando…

NADPH oxidase is the major source of placental superoxide in early pregnancy: association with MAPK pathway activation

First-trimester placenta (<10 gestational weeks (GW)) develops in a low oxygen environment (≈2%). Early oxygen exposure can cause oxidative damage leading to pregnancy disorders. The aim of this work was to determine the major sources of placental superoxide during early pregnancy - more specific...

Descripción completa

Detalles Bibliográficos
Autores principales: Hernandez, Isabelle, Fournier, Thierry, Chissey, Audrey, Therond, Patrice, Slama, Abdel, Beaudeux, Jean-Louis, Zerrad-Saadi, Amal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764989/
https://www.ncbi.nlm.nih.gov/pubmed/31562365
http://dx.doi.org/10.1038/s41598-019-50417-4