Intestinal inflammation increases convulsant activity and reduces antiepileptic drug efficacy in a mouse model of epilepsy

We studied the effects of intestinal inflammation on pentylenetetrazole (PTZ)-induced seizures in mice and the effects thereon of some antiepileptic and anti-inflammatory treatments to establish if a link may exist. The agents tested were: alpha-lactoalbumin (ALAC), a whey protein rich in tryptophan...

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Detalles Bibliográficos
Autores principales: De Caro, Carmen, Leo, Antonio, Nesci, Valentina, Ghelardini, Carla, di Cesare Mannelli, Lorenzo, Striano, Pasquale, Avagliano, Carmen, Calignano, Antonio, Mainardi, Paolo, Constanti, Andrew, Citraro, Rita, De Sarro, Giovambattista, Russo, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764994/
https://www.ncbi.nlm.nih.gov/pubmed/31562378
http://dx.doi.org/10.1038/s41598-019-50542-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764994/
https://www.ncbi.nlm.nih.gov/pubmed/31562378
http://dx.doi.org/10.1038/s41598-019-50542-0

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