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Tissue-resident memory CD8(+) T cells amplify anti-tumor immunity by triggering antigen spreading through dendritic cells

Tissue-resident memory CD8(+) T (Trm) cells mediate potent local innate and adaptive immune responses and play a central role against solid tumors. However, whether Trm cells cross-talk with dendritic cells (DCs) to support anti-tumor immunity remains unclear. Here we show that antigen-specific acti...

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Detalles Bibliográficos
Autores principales: Menares, Evelyn, Gálvez-Cancino, Felipe, Cáceres-Morgado, Pablo, Ghorani, Ehsan, López, Ernesto, Díaz, Ximena, Saavedra-Almarza, Juan, Figueroa, Diego A., Roa, Eduardo, Quezada, Sergio A., Lladser, Alvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765014/
https://www.ncbi.nlm.nih.gov/pubmed/31562311
http://dx.doi.org/10.1038/s41467-019-12319-x