IL-6 Activities in the Tumour Microenvironment. Part 1

The predominant role of IL-6 in cancer is its key promotion of tumour growth. IL-6 binds IL-6 receptor (IL-6R) and the membrane-bound glycoprotein gp130. The complex I-6/IL-6R/gp130 starts the Janus kinases (JAKs) and signal transducer and activator of transcription 3 (STAT3) or JAK/STAT3 pathway. I...

Descripción completa

Detalles Bibliográficos
Autores principales: Chonov, Dimitur Chavdarov, Ignatova, Maria Magdalena Krasimirova, Ananiev, Julian Rumenov, Gulubova, Maya Vladova
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765074/
https://www.ncbi.nlm.nih.gov/pubmed/31592285
http://dx.doi.org/10.3889/oamjms.2019.589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765074/
https://www.ncbi.nlm.nih.gov/pubmed/31592285
http://dx.doi.org/10.3889/oamjms.2019.589

Ejemplares similares