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IL-6 Activities in the Tumour Microenvironment. Part 1

The predominant role of IL-6 in cancer is its key promotion of tumour growth. IL-6 binds IL-6 receptor (IL-6R) and the membrane-bound glycoprotein gp130. The complex I-6/IL-6R/gp130 starts the Janus kinases (JAKs) and signal transducer and activator of transcription 3 (STAT3) or JAK/STAT3 pathway. I...

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Detalles Bibliográficos
Autores principales:	Chonov, Dimitur Chavdarov, Ignatova, Maria Magdalena Krasimirova, Ananiev, Julian Rumenov, Gulubova, Maya Vladova
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Republic of Macedonia 2019
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765074/ https://www.ncbi.nlm.nih.gov/pubmed/31592285 http://dx.doi.org/10.3889/oamjms.2019.589

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